A “GAME” changer in plant secondary metabolism
Plant Science Research WeeklyCholesterol, an essential structural component of membranes and a precursor for steroid hormones, serves as a key metabolite at the interface of primary and secondary metabolism. However, the mechanisms regulating the balance between its diverse downstream metabolic pathways remain poorly understood.…
Review. Decoding resilience: Ecology, regulation, and evolution of biosynthetic gene clusters
Plant Science Research WeeklyAlthough clusters of functionally related genes are common in prokaryotes, until recently it was thought that they were not a feature of eukaryotic genomes. However, several studies have identified biosynthetic gene clusters (BGCs) in plants. Many of these gene clusters include sets of enzymes that act…
PCMD: an interactive library for comparative metabolomics studies
Plant Science Research WeeklyAlbert Einstein once said, “The only thing that you absolutely have to know is the location of the library.” Libraries house vast troves of information for readers to explore, analyze, and use. With the exponential increase in data, libraries have also evolved into digital databases and online platforms.…
Phloem loading and subcellular transport drive carbon storage in cassava roots
Plant Science Research WeeklyCassava (Manihot esculenta) is a vital starchy crop essential for food security in Sub-Saharan Africa, South America, and Southeast Asia. A recent study on cassava by Rüscher et al. provides important insights into the plant’s sugar control mechanisms as the roots expand, produce large amounts of…
Triacylglycerol remodeling to synthesize unusual fatty acids in plants
Plant Science Research WeeklyPlant oils, composed of fatty acids, provide humans and animals with food, essential nutrients, chemicals, and biofuels. Plants accumulate over 450 “unusual” fatty acids, which could hold significant value if they achieve optimal production. Hydroxylated fatty acids (HFA) are unusual fatty acids…
Unlocking nature’s arsenal: Engineering grasses for insect defense and livestock palatability
Plant Science Research WeeklyThe defensive alkaloid gramine, present in barley and other grass species, plays an important role in protecting the plant from insect damage but poses challenges for ruminant palatability. Breeding strategies balance these factors by maintaining the protective function and making the grain palatable…
Understanding the role of metabolites in the evolution of C4 photosynthesis
Plant Science Research WeeklyPlants that use C4 photosynthesis, whereby carbon is concentrated around RuBisCo in bundle sheath cells, have high water and nitrogen use efficiencies. Thus, understanding how C4 photosynthesis evolves is of much interest. The Flaveria genus provides a unique opportunity for this, as it contains species…
SIMPEL tool to elucidate dynamics of complex metabolism
Plant Science Research WeeklyCellular metabolism involves flux through metabolic routes, which can be measured using stable isotope (13C,15N) tracers. High-resolution mass spectrometry (HRMS) and transient isotope labeling studies offer an opportunity to get an in-depth understanding of metabolism in specific contexts. In this new…
UMAMIT44 exports plastidial glutamate and is essential for plant growth
Plant Science Research WeeklyAmino acids (AA) are fundamental components of peptides, proteins, and enzymes that play a critical role in plant growth, cellular metabolism, and stress response. Plants synthesize most AA within chloroplasts and require membrane transporters to transfer them from stroma to cytosol. Cytosolic AA are…