Plant rheostat BAP2 determines the direction of ER stress tolerance mechanisms
Plant Science Research WeeklyWhen protein folding is disrupted by abiotic or biotic stresses, cells can experience ER stress. Sensors like inositol-requiring enzyme 1 (IRE1) detect this stress, triggering the unfolded protein response (UPR) pathway. UPR signaling activates genes that restore proteostasis and maintain cellular vitality.…
A biosensor for ER redox dynamics highlights ER oxidoreductins
The Plant Cell: In a NutshellUgalde et al. report that dynamic monitoring of the ER luminal glutathione redox potential highlights the role of ER oxidoreductins in defining redox conditions and the interplay between different redox inputs during hypoxia and reductive stress. Plant Cell https://doi.org/10.1093/plcell/koac202
Background:…