Shugang Hui: Plant Physiology First Author

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Shugang Hui, first author of “Rice microRNA156/529-SQUAMOSA PROMOTER BINDING PROTEIN-LIKE7/14/17 modules regulate defenses against bacteria”

Current Position: Postdoc, National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan), Hubei Hongshan Laboratory, Huazhong Agricultural University

Education: Ph. D., Huazhong Agricultural University

Non-scientific Interests: Reading and travelling

Brief bio: Throughout my postgraduate studies, I had the opportunity to work closely with Professor Shiping Wang and her research group. During this time, my research focused on elucidating the molecular mechanisms of sulfate inhibit the virulence of Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas oryzae pv. oryzicola (Xoc) in rice. Additionally, I investigated the pathogenic mechanisms of TALEs, which are essential virulence factors in various plant pathogenic bacteria. The findings of my research were published in prestigious journals such as molecular plant, molecular plant pathology, and plant science, and have helped to advance our understanding of rice disease resistance.

I am currently working as a postdoctoral fellow in the lab of professor Meng Yuan at the national key laboratory of crop genetic improvement. Our study revealed that the bacterial pathogens Xoo and Xoc activate the expressions of miR156 and miR529, which in turn suppress the transcriptions of OsSPL7, OsSPL14, and OsSPL17. Down-regulated these OsSPLs could not efficiently activate the transcriptions of their downstream target genes OsAOS2 and OsNPR1, leading to decreased JA accumulation and weakened SA signaling pathway, respectively, which facilitate the infection of Xoo or Xoc. The revealed miR156/529-OsSPL7/14/17-OsAOS2/OsNPR1 regulatory network provides a potential strategy to improve rice resistance by suppressing miR156/529 expression or enhancing OsSPL7/14/17 expression.

姓名：惠述刚

目前职位：华中农业大学作物遗传改良全国重点实验室，博士后

教育背景：华中农业大学，博士

兴趣爱好：阅读，旅游

个人简介：本人研究生期间在王石平老师的指导下详细解析了硫酸根离子抑制水稻白叶枯病菌和细菌性条斑病菌致病力的机制以及TALE的致病机制，相关工作发表于Molecular plant，Molecular plant pathology和Plant science等杂志。

我现在在作物遗传改良全国重点实验室袁猛老师实验室做博士后。我们的研究发现水稻白叶枯病菌和细菌性条斑病菌激活miR156和miR529的表达，这两种miRNA会抑制OsSPL7、OsSPL14和OsSPL17的转录。下调OsSPL7/14/17的表达，无法有效地激活他们的下游靶基因OsAOS2和OsNPR1的转录，导致水稻中的茉莉酸含量减少，同时也削弱了水杨酸信号转导通路，从而有利于白叶枯病菌和细菌性条斑病菌的侵染。我们的研究揭示了miR156/529-OsSPL7/14/17-OsAOS2/OsNPR1调控网络参与水稻抗病的机制，为通过抑制miR156/529表达或增强OsSPL7/14/17表达培育抗病水稻品种提供了理论基础。