Peng Li: Plant Physiology First Author

Peng Li, first author of “Peronophythora litchii RXLR effector PlAvh202 destabilizes a host ethylene biosynthesis enzyme” 

Current Position: PhD candidate at Guangdong Key Laboratory of Microbial Signals and Disease Control, South China Agricultural University

Education: 2015.09–2018.06, Master degree of Agriculture, Henan Institute of Science and Technology

2018.09– , PhD candidate, South China Agricultural University

Non-scientific Interests: Music, Hiking

Brief biography: The interaction between host plants and pathogens became my interest and research subject, since I joined the Guangdong Key Laboratory of Microbial Signals and Disease Control, a dynamic team supervised by professor Zide Jiang of South China Agricultural University. In our study, a RXLR effector PlAvh202 secreted by Peronophythora litchii was used as a molecular probe to explore the mechanism of plant immunity. By Co-IP, LC-MS/MS, GST-Pull down, SLC, and ethylene quantification, we identified a plant target of PlAvh202 and revealed the mechanism that PlAvh202 targets and destabilizes SAMS by 26S proteasome, leading to the suppression of ethylene-mediated pathogen resistance. We firstly found that SAMS could be captured and destabilized by oomycete RXLR effector, which is distinct from previous studies that virus interfered with plant resistance by altering the enzyme activity of SAMS. Our study provides a new potential target for plant resistance breeding.

第一作者：李鹏

目前职位：华南农业大学微生物信号与病害防控重点实验室，博士研究生

教育经历：2015.09–2018.06，河南科技学院硕士研究生

2018.09至今，华南农业大学微生物信号与病害防控重点实验室，博士研究生

兴趣爱好：音乐，徒步旅行

个人简历：自师从姜子德教授并加入华南农业大学微生物信号与疾病防控重点实验室后，我主要从事病原菌与寄主植物互作机制的研究。我们是一个充满活力的团队，并且我对目前的研究有着浓厚的兴趣。本研究利用荔枝霜疫霉分泌的一个RXLR效应蛋白作为探针，探究植物免疫机制。通过免疫共沉淀、液相色谱串联质谱、GST pull-down、萤火素酶互补和乙烯定量等实验，我们鉴定到了PlAvh202在寄主植物中的靶标，并揭示了其作用机制：PlAvh202与植物中的SAMS互作，促进26S蛋白酶体依赖的SAMS降解，最终抑制了乙烯介导的植物抗病能力。与病毒干扰SAMS酶活力机制不同的是，我们首次发现卵菌RXLR效应分子可以靶向SAMS蛋白，并促进其降解。我们的研究为荔枝抗病育种提供了一个新的潜在靶标。