Minqi Yang: The Plant Cell First Author

Minqi Yang, co-first author of “Binding by the Polycomb complex component BMI1 and H2A monoubiquitination shape local and long-range interactions in the Arabidopsis genome”

Current Position: Ph.D. candidate, School of Advanced Agricultural Sciences, Peking University

Education: Bachelor of ­­­­Science, School of ­­­Life Sciences, Sun Yat-Sen University, Guangzhou, People’s Republic of China

Non-scientific Interests: photographing and hiking

 

Brief bio: How does the cell fold and compress the genetic material in the narrow nucleus, and how does it efficiently and orderly regulate the genetic material to complete various life activities? This is the question that fascinates me most in the field of plant epigenetic research. I was struck by the ingenuity of the chromatin conformation capture technology that was needed to study this problem. Using this technology to explore the life activities of cells, especially plant cells, will be the interest of my doctoral research. As biological research enters the era of omics, the requirement for data analysis is further raised. In 2021, I joined the group of Dr. Yue Zhou in Peking University and studied bioinformatics under the guidance of Dr. Yue Zhou and Dr. Hang He. In this study, we further determined the three-dimensional structural hierarchy of Arabidopsis thaliana and identified the regulatory role of PRC1 in it.

 

姓名：杨敏琪

目前职位：北京大学，博士研究生

教育经历：中山大学生命科学学院，理学学士

兴趣爱好：摄影，徒步

个人简介：细胞如何将遗传物质盘曲折叠压缩在狭小的细胞核中，又如何高效有序地调控遗传物质完成各类生命活动？这是植物表观研究领域最吸引我的问题。研究这个问题所需要借助的染色质构象捕捉技术，其设计思路的巧妙让我深受震撼。借助这项技术对细胞，尤其是植物细胞的生命活动做出探索，将是我博士研究阶段的兴趣所在。随着生物研究进入组学时代，对数据分析的要求也进一步提升。2021年我加入北京大学周岳研究员课题组，在周岳老师和何航老师的指导下学习生物信息学。在本研究中，我们进一步确定了拟南芥的三维结构层次，并确定了PRC1在其中的调控作用。