Haodong Huang: The Plant Cell First Author

Haodong Huang, co-first author of “An ancestral role for 3-KETOACYL-COA SYNTHASE3 as a negative regulator of plant cuticular wax synthesis”

Current Position: Ph.D. student, Hubei University

Education: Master, Hubei University

Non-scientific Interests: Cooking, Reading, Running

Brief bio: I have been interested in the growth of plants and the adaptation to the environment since my undergraduate course. In 2019, I became a master’s student of Professor Shiyou Lü, College of Life Science, Hubei University, Wuhan, China. In 2022, after receiving my master’s degree, I continued to study for a doctor’s degree under supervision of Professor Shiyou Lü. My research mainly focuses on understanding the role of 3-KETOACYL-COA SYNTHASEs (KCSs) in Arabidopsis surface lipid synthesis. We found that Arabidopsis KCS3 previously shown to lack canonical catalytic activity instead functions as a negative regulator in wax metabolism by reducing the enzymatic activity of KCS6, a key KCS involved in wax production. At present, I continue to identify the roles of additional KCSs lacking FAE activity, seek the possible regulatory targets of these KCSs, and determine their biological function in response to different environments.

 

共同第一作者：黄浩东

现在职位：湖北大学，博士在读

教育经历：湖北大学，硕士

兴趣爱好：烹饪、读书、跑步

个人简介：从本科开始我就对植物的生长和对环境的适应产生兴趣，2019年，我成为湖北大学生命科学学院吕世友教授的硕士研究生，在2022年获得硕士学位后，继续跟随吕世友教授攻读博士学位。我的研究主要集中在解析3-酮酰基辅酶A合成酶（KCS）家族基因在拟南芥表皮脂类合成中的作用。我们最新发现，尽管拟南芥中的KCS3不具有典型的催化超长链脂肪酸延伸的酶活性，但是该蛋白可以通过降低KCS6（参与蜡质合成的关键KCS）的酶活性而负调节蜡质的合成。目前，我正在继续解析其他缺乏典型FAE酶活性的KCS成员的功能，寻找这些KCS可能的调控目标，并确定它们在响应不同环境因子过程中的生物功能。