Gibberellin-mediated PtrLBD39–PtrHDA6–PtrHCT epigenetic path regulates lignin biosynthesis during tension wood formation in Populus trichocarpa
UncategorizedAbstractTension wood (TW) is a specialized xylem tissue formed in angiosperm trees to counteract mechanical stresses. Increased phytohormones, particularly gibberellins (GAs), and decreased lignin deposition are two well-established features of TW, yet the molecular mechanisms linking GA signaling to…
Spatial and Single-Nucleus Transcriptomic Profiling Reveal Polarity and Intracellular Responses to Mitochondrial Dysfunction
UncategorizedAbstractOrganelle retrograde signaling studies have exclusively relied on bulk tissues, obscuring cell-type specificity, spatial organization, and heterogeneity within cell types. Here, we use single-nucleus and spatial RNA sequencing to define the cellular and spatial architecture of mitochondrial stress…
A hierarchically organized ARF–MADS module integrates auxin signaling into floral organ identity networks
UncategorizedAbstractFloral organ identity specification and subsequent organ differentiation are generally regarded as distinct developmental processes, yet the mechanisms connecting these programs remain poorly understood. In orchids, the P code explains how higher-order MADS-box complexes specify sepal, petal,…
AraVirusPPI: A protein language model-powered method for predicting Arabidopsis thaliana-virus protein-protein interactions
UncategorizedAbstractPlant-virus protein-protein interactions (PPIs) play crucial roles in viral infection and host immune responses. However, large-scale experimental characterization of plant-virus PPIs is costly and labor-intensive, suggesting the need to develop computational methods. Recent advances in biological…
Postdoctoral Position in Statistical Genetics | Mass General Brigham
UncategorizedBoston, Massachusetts, Applications are invited for a joint postdoctoral position with Dr. Liming Liang, Professor at the Harvard School of Public Health, and Dr. Michael Cho, Associate Professor at Harvard Medical School and the Channing Division of Network Medicine at Brigham and Women's Hospital,…