Entries by Nathan Scinto-Madonich

Natural Herbicide: Cyanobacterial antimetabolite inhibits the growth of prototrophic organisms (Nature Comms)

The shikimate pathway synthesizes aromatic amino acids in microorganisms and plants, and its absence in animals makes the shikimate pathway a common target for the development of herbicides. Brilisauer et al. 2019 isolated a novel compound from the cyanobacterium Synechococcus elongatus—7-deoxy-sedoheptulose (7dSH)—that blocks 3-deoxy-D-arabino-heptulosonate 7-phospate (DAHP) from binding to 3-dehydroquinate (DHQ) synthase, a key step […]

Auxin efflux carrier ZmPGP1 mediates root growth inhibition under aluminum stress (Plant Physiology)

Acid soils (pH < 5.5) mobilize aluminum (Al) in the rhizosphere, which damages the root meristem and hinders exploration for nutrients and water. Zhang et al. demonstrate that a mutation in ZmPGP1, an auxin transport protein, imparts enhanced root growth under toxic Al conditions. The enhanced root growth is attributed to greater auxin accumulation, which […]