Single cell transcriptomics aids gene discovery of complex natural product biosynthesis
From an ancient Greek cure-all to a modern treatment for mild depression, Hypericum perforatum (St. John’s wort) is a fascinating weed. Its leaves and flowers produce hyperforin, a metabolite derived from the isoprenoid pathway, which acts as a serotonin reuptake inhibitor. Despite partial genome and transcriptome data, the later steps in its biosynthesis pathway remain […]